Medical comorbidities and dementia diagnostic outcomes in African American and Hispanic individuals enrolled in DAWN
Cardiovascular and metabolic conditions significantly increase the risk of classification as cognitively affected in community dwelling HI and AA individuals. Of note, this risk did not differ between our HI and AA groups. These results suggest the need to raise awareness about the impact of medical comorbidities on brain health in HI and AA communities. Such comorbidities represent preventable and reversible risk factors for cognitive decline. An important next step will be to integrate these phenotypes into genetic studies of ADRDs.
Authors
- Gary W. Beecham (ORCID: https://orcid.org/0000-0002-7061-6332)
- Michael L. Cuccaro (ORCID: https://orcid.org/0000-0003-4769-0785)
- Kara L. Hamilton‐Nelson (ORCID: https://orcid.org/0000-0003-3748-7193)
- Katrina Celis
- Jeffery M. M Vance
- Briseida E. Feliciano‐Astacio (ORCID: https://orcid.org/0000-0003-4747-8928)
- Michael B. Prough
- Pedro Mena (ORCID: https://orcid.org/0000-0003-2150-2977)
- Glenies S Valladares
- Katalina McInerney
- Margaret Pericak‐Vance
- Andrew F Zaman
- Vanessa C. Rodriguez
- Jose J. Sanchez
- Larry D Adams
- Farid Rajabli
Institutions
- University of Miami (US)
- Central University of the Caribbean (PR)
- Dr. John T. Macdonald Foundation (US)
- Wake Forest University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_106956
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00