Characterising real‐world macro walking outcomes of people with Posterior Cortical Atrophy using accelerometery: Feasibility and preliminary comparison with Alzheimer's and Lewy body disease

All PCA participants completed real-world walking assessment for the recommended period of >3 days, suggesting feasibility. Preliminary results suggest that the PCA group's real-world macro walking behaviours are more similar to AD than LBD. Despite a small sample, this novel data provides proof-of-concept. Only real-world macro walking outcomes are reported. Previously, clinic-based accelerometery outcomes relating to micro gait characteristics (e.g. spatiotemporal and signal-based features) were more sensitive to differences between LBD and AD; this will be further explored for PCA.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70863_110506
Primary Topic
Balance, Gait, and Falls Prevention
Type
article
Field-Weighted Citation Impact
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article

Characterising real‐world macro walking outcomes of people with Posterior Cortical Atrophy using accelerometery: Feasibility and preliminary comparison with Alzheimer's and Lewy body disease

L. Rochester, Cameron Kirk, Silvia Del Din, Matthew J. Bancroft et al.
Alzheimer s & Dementia
Balance, Gait, and Falls Prevention
article

Characterising real‐world macro walking outcomes of people with Posterior Cortical Atrophy using accelerometery: Feasibility and preliminary comparison with Alzheimer's and Lewy body disease

L. Rochester, Cameron Kirk, Silvia Del Din, Matthew J. Bancroft, Brook Galna, Ríona Mc Ardle, Kaski Diego, Yuhan Bai, Keir X X Yong, Alan J Thomas, Jonathan D. Rohrer
article en

Abstract

All PCA participants completed real-world walking assessment for the recommended period of >3 days, suggesting feasibility. Preliminary results suggest that the PCA group's real-world macro walking behaviours are more similar to AD than LBD. Despite a small sample, this novel data provides proof-of-concept. Only real-world macro walking outcomes are reported. Previously, clinic-based accelerometery outcomes relating to micro gait characteristics (e.g. spatiotemporal and signal-based features) were more sensitive to differences between LBD and AD; this will be further explored for PCA.

Alzheimer s & DementiaVol. 21(S9)
Queen Mary University of London (GB), Murdoch University (AU), National Institute for Health and Care Excellence (GB), UK Dementia Research Institute (GB), NIHR Newcastle Biomedical Research Centre (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB), Newcastle University (GB)
Openalex Percentile: Top 24%
Balance, Gait, and Falls Prevention
DOIOpen Access PDFOpenAlex
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Characterising real‐world macro walking outcomes of people with Posterior Cortical Atrophy using accelerometery: Feasibility and preliminary comparison with Alzheimer's and Lewy body disease — L. Rochester, Cameron Kirk, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS