Urothelial genotoxicity of household chemicals in healthy canine urinary bladder organoids relative to observed urinary exposures in pet dogs
Acrolein and 2,6-DMA could reach genotoxic urinary concentrations after household exposures in some pet dogs, and the role of 2,6-DMA in canine bladder cancer risk deserves assessment in a larger sample size.
Authors
- Lauren A. Trepanier (ORCID: https://orcid.org/0000-0001-8585-7350)
- Christopher Zdyrski (ORCID: https://orcid.org/0000-0002-7556-5298)
- Allenspach Karin
- Hannah Peterson (ORCID: https://orcid.org/0000-0001-5031-9384)
- J. Mochel
Institutions
- University of Wisconsin–Madison (US)
- University of Georgia (US)
- Iowa State University (US)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-12-23
- DOI
- https://doi.org/10.3389/fvets.2025.1702980
- Primary Topic
- Arsenic contamination and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Purdue University
- Massachusetts Institute of Technology