Longitudinal cardiovascular risks and their impact on white matter hyperintensities
The impact of CVR on WMH differs by sex, with women showing greater effects on water content and men more on myelin integrity. These findings suggest that sex-specific approaches may be needed for understanding and targeting cardiovascular risk factors to preserve white matter health and prevent cognitive decline.
Authors
- Antoine Lutti (ORCID: https://orcid.org/0000-0003-3281-5477)
- Aurélie Bussy (ORCID: https://orcid.org/0000-0001-6695-9941)
- Camille Cathala
- Bogdan Draganski
- Ferath Kherif
Institutions
- University Hospital of Bern (CH)
- Centre Hospitalier Universitaire Vaudois (CH)
- Hôpital Orthopédique de la Suisse Romande (CH)
- École Polytechnique Fédérale de Lausanne (CH)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110114
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00