Post‐TBI cognitive trajectories: Differences by sex/gender, cause, and severity

In the fully adjusted model, years-since-TBI was statistically significantly associated with a decrease in cognition (b = -0.05, p = 0.008). Interpersonal violence as the cause of TBI was also negatively associated with cognition (b = -0.74, p = 0.004). Neither sex/gender nor TBI sequelae had a statistically significant association with cognition CONCLUSION: TBI may have long-lasting effects on cognitive health well after its occurrence, and these may be compounded when that injury is due to interpersonal violence. More research is needed to analyze the relationship between violence, TBI, and later-life cognition.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_107614
Primary Topic
Traumatic Brain Injury Research
Type
article
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article

Post‐TBI cognitive trajectories: Differences by sex/gender, cause, and severity

D. Hanes, Sean A.P. Clouston
Alzheimer s & Dementia
Traumatic Brain Injury Research
article

Post‐TBI cognitive trajectories: Differences by sex/gender, cause, and severity

D. Hanes, Sean A.P. Clouston
article en

Abstract

In the fully adjusted model, years-since-TBI was statistically significantly associated with a decrease in cognition (b = -0.05, p = 0.008). Interpersonal violence as the cause of TBI was also negatively associated with cognition (b = -0.74, p = 0.004). Neither sex/gender nor TBI sequelae had a statistically significant association with cognition CONCLUSION: TBI may have long-lasting effects on cognitive health well after its occurrence, and these may be compounded when that injury is due to interpersonal violence. More research is needed to analyze the relationship between violence, TBI, and later-life cognition.

Alzheimer s & DementiaVol. 21(S6)
University of Toronto (CA), Stony Brook School (US), Public Health Ontario (CA), Stony Brook University (US)
Quality Education
Openalex Percentile: Top 30%
Traumatic Brain Injury Research
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