Four new glycoside compounds from <i>Sinapis alba</i> L. and their cytotoxic activity

Four novel compounds, 4-hydroxybenzyl-7-<i>S</i>-<i>β</i>-glucopyranoside (1), 4-hydroxybenzyl-7-<i>S</i>-<i>S</i>-<i>β</i>-glucopyranoside (2), 1-<i>S</i>-(4'-hydroxybenzyl)-6-(4''-hydroxybenzoyl)-<i>β</i>-glucopyranoside (3), and 1-<i>O</i>-(4'-hydroxybenzoyl)-2-<i>O</i>-Z-sinapoyl-<i>β</i>-glucopyranoside (4) were used to isolate from <i>Sinapis alba</i> L. seeds. The structures were accomplished through spectroscopic analysis (NMR and MS) corroborated by chemical studies. Three human cancer cell lines were employed to detect the cytotoxic effects of the compounds.

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Publication Details

Journal
Natural Product Research
Published
2025-12-23
DOI
https://doi.org/10.1080/14786419.2025.2602196
Primary Topic
Phytochemistry and Biological Activities
Type
article
Field-Weighted Citation Impact
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article

Four new glycoside compounds from Sinapis alba L. and their cytotoxic activity

Linlin Ni, Xiaoyu Wang, Xinyu Shi, Degang Kong et al.
Natural Product Research
Phytochemistry and Biological Activities
article

Four new glycoside compounds from Sinapis alba L. and their cytotoxic activity

Linlin Ni, Xiaoyu Wang, Xinyu Shi, Degang Kong, Meichao Cai, Honglei Zhou, Xiaoni Kong
article en

Abstract

Four novel compounds, 4-hydroxybenzyl-7-<i>S</i>-<i>β</i>-glucopyranoside (1), 4-hydroxybenzyl-7-<i>S</i>-<i>S</i>-<i>β</i>-glucopyranoside (2), 1-<i>S</i>-(4'-hydroxybenzyl)-6-(4''-hydroxybenzoyl)-<i>β</i>-glucopyranoside (3), and 1-<i>O</i>-(4'-hydroxybenzoyl)-2-<i>O</i>-Z-sinapoyl-<i>β</i>-glucopyranoside (4) were used to isolate from <i>Sinapis alba</i> L. seeds. The structures were accomplished through spectroscopic analysis (NMR and MS) corroborated by chemical studies. Three human cancer cell lines were employed to detect the cytotoxic effects of the compounds.

Natural Product Research
Shandong University of Traditional Chinese Medicine (CN), Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 25%
Phytochemistry and Biological Activities
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