Relationship between Alzheimer's disease polygenic risk score and the effects of multidomain lifestyle intervention: the SUPERBRAIN‐MEET subanalysis
Our study demonstrates that the effectiveness of multidomain interventions may be influenced by an individual's genetic risk for AD. Specifically, the multidomain lifestyle intervention appears to be more beneficial for individuals with a higher genetic risk of AD, particularly APOE ε4 carriers with a high PRS.
Authors
- Jee Hyang Jeong (ORCID: https://orcid.org/0000-0001-7945-6956)
- Joohon Sung (ORCID: https://orcid.org/0000-0001-9948-0160)
- So Young Moon
- Jiyun Hwang
- Seong Hye Choi
Institutions
- Ewha Womans University (KR)
- Seoul National University (KR)
- Inha University (KR)
- Ajou University (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_107759
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00