Modeling amyloid therapy potential on a population level: An adaptation of the MISCAN‐Dementia model
We are adapting the MISCAN-Dementia model to estimate the population-wide impact of amyloid-targeting therapies. In this presentation, we will present the model changes and methodological considerations we have encountered, as well as first estimates of the eligible population. To capture the impact of amyloid-targeting therapies fully, the next steps include estimating the population-wide harms and benefits of amyloid-targeting therapies.
Authors
- Inge MCM de Kok
- Chiara C. Brück (ORCID: https://orcid.org/0000-0001-5677-269X)
- Everard G.B. Vijverberg (ORCID: https://orcid.org/0000-0003-3879-884X)
- Frank J. Wolters
Institutions
- Erasmus MC (NL)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_105453
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00