Modeling amyloid therapy potential on a population level: An adaptation of the MISCAN‐Dementia model

We are adapting the MISCAN-Dementia model to estimate the population-wide impact of amyloid-targeting therapies. In this presentation, we will present the model changes and methodological considerations we have encountered, as well as first estimates of the eligible population. To capture the impact of amyloid-targeting therapies fully, the next steps include estimating the population-wide harms and benefits of amyloid-targeting therapies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_105453
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Modeling amyloid therapy potential on a population level: An adaptation of the MISCAN‐Dementia model

Inge MCM de Kok, Chiara C. Brück, Everard G.B. Vijverberg, Frank J. Wolters
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Modeling amyloid therapy potential on a population level: An adaptation of the MISCAN‐Dementia model

Inge MCM de Kok, Chiara C. Brück, Everard G.B. Vijverberg, Frank J. Wolters
article en

Abstract

We are adapting the MISCAN-Dementia model to estimate the population-wide impact of amyloid-targeting therapies. In this presentation, we will present the model changes and methodological considerations we have encountered, as well as first estimates of the eligible population. To capture the impact of amyloid-targeting therapies fully, the next steps include estimating the population-wide harms and benefits of amyloid-targeting therapies.

Alzheimer s & DementiaVol. 21(S6)
Erasmus MC (NL), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), Vrije Universiteit Amsterdam (NL)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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Modeling amyloid therapy potential on a population level: An adaptation of the MISCAN‐Dementia model — Inge MCM de Kok, Chiara C. Brück, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS