Pregnancy-related acute kidney injury in south India: Clinical profile and maternal outcomes

Pregnancy-related acute kidney injury (PR-AKI) is an uncommon but serious complication that poses significant maternal and foetal risks. This retrospective study analysed 83 cases of PR-AKI to evaluate causes, clinical features, and outcomes. Overall, 71% recovered, 23% developed chronic kidney disease (CKD), and 6% died. Thrombotic microangiopathy carried the highest CKD risk (85%), while sepsis caused most deaths (27%). Patients who could be managed conservatively recovered fully, whereas those more severe illness requiring dialysis inevitably had less favourable outcomes. Early recognition of high-risk conditions and timely intervention can therefore improve renal recovery and maternal survival.

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Journal
Tropical Doctor
Published
2025-12-23
DOI
https://doi.org/10.1177/00494755251406688
Primary Topic
Acute Kidney Injury Research
Type
article
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article

Pregnancy-related acute kidney injury in south India: Clinical profile and maternal outcomes

Jeeja Jaya Janardhanan, Thotanolla Surya Prakash, Namesh Kamat
Tropical Doctor
Acute Kidney Injury Research
article

Pregnancy-related acute kidney injury in south India: Clinical profile and maternal outcomes

Jeeja Jaya Janardhanan, Thotanolla Surya Prakash, Namesh Kamat
article en

Abstract

Pregnancy-related acute kidney injury (PR-AKI) is an uncommon but serious complication that poses significant maternal and foetal risks. This retrospective study analysed 83 cases of PR-AKI to evaluate causes, clinical features, and outcomes. Overall, 71% recovered, 23% developed chronic kidney disease (CKD), and 6% died. Thrombotic microangiopathy carried the highest CKD risk (85%), while sepsis caused most deaths (27%). Patients who could be managed conservatively recovered fully, whereas those more severe illness requiring dialysis inevitably had less favourable outcomes. Early recognition of high-risk conditions and timely intervention can therefore improve renal recovery and maternal survival.

Tropical DoctorVol. 56(2)
Sri Venkateswara Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 32%
Acute Kidney Injury Research
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