Pediatric reference values for glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon in children and adolescents
This study provides age- and sex-specific reference values for glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon in children and adolescents. This is the first publication presenting percentiles and z-scores for GLP-1 and GIP in children which is of value for future pediatric comparisons. Knowledge about normal physiology is of major importance for future research in the upcoming area of GLP-1, GIP and glucagon as potential biomarkers for metabolic disorders.
Authors
- Malene Heidemann (ORCID: https://orcid.org/0000-0002-6345-3264)
- Freja B. Mørk (ORCID: https://orcid.org/0000-0002-6444-2049)
- Verena Hirschberg (ORCID: https://orcid.org/0000-0002-3600-1430)
- Niels Wedderkopp (ORCID: https://orcid.org/0000-0002-9660-6618)
- Trine Witzner Hessel Lawaetz
- Amalie Dalgas-Madsen
- Andreas Kryger Jensen
- Flemming Pociot
- Jesper Johannesen
- Anders Jørgen Shou
Institutions
- University of Copenhagen (DK)
- Steno Diabetes Centers (DK)
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Herlev Hospital (DK)
- Gentofte Hospital (DK)
Publication Details
- Journal
- Pediatric Research
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1038/s41390-025-04551-7
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Steno Diabetes Center Copenhagen