Uterine Lipoleiomyoma: Case Report and Review

Uterine lipoleiomyoma is a rare benign tumor composed of smooth muscle and mature adipose tissue. We report a case of a 53-year-old perimenopausal woman who presented with vaginal spotting for 2 months. Transvaginal ultrasonography revealed a hyperechoic submucosal mass with a hypoechoic rim at the anterior uterine wall measuring 37 × 39 mm. Hysteroscopic resection was performed, and histopathology confirmed lipoleiomyoma characterized by bland spindle cells mixed with mature adipocytes and thick-walled blood vessels. The patient recovered uneventfully and remained asymptomatic during follow-up. This case highlights the importance of recognizing this rare benign variant of leiomyoma, particularly in perimenopausal women.