Ketogenic Diet Therapy for Adult Febrile Infection-Related Epilepsy Syndrome (FIRES): A Case Series of Five Patients and Clinical Efficacy Analysis

FIRES is a rare and devastating clinical syndrome with an unclear pathogenesis, high mortality, and poor prognosis, often accompanied by cognitive decline or severe neurological sequelae. KD appears effective in FIRES management; however, due to limited case data, further large-sample, prospective, or randomized controlled studies are needed to elucidate its short- and long-term efficacy in adult FIRES patients.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-12-01
DOI
https://doi.org/10.2147/idr.s574683
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Ketogenic Diet Therapy for Adult Febrile Infection-Related Epilepsy Syndrome (FIRES): A Case Series of Five Patients and Clinical Efficacy Analysis

Y C Li, Yanhong Wang, Minghua Fan, Haiyan Diao
Infection and Drug Resistance
Diet and metabolism studies
article

Ketogenic Diet Therapy for Adult Febrile Infection-Related Epilepsy Syndrome (FIRES): A Case Series of Five Patients and Clinical Efficacy Analysis

Y C Li, Yanhong Wang, Minghua Fan, Haiyan Diao
article en

Abstract

FIRES is a rare and devastating clinical syndrome with an unclear pathogenesis, high mortality, and poor prognosis, often accompanied by cognitive decline or severe neurological sequelae. KD appears effective in FIRES management; however, due to limited case data, further large-sample, prospective, or randomized controlled studies are needed to elucidate its short- and long-term efficacy in adult FIRES patients.

Infection and Drug ResistanceVol. Volume 18
Shanxi Academy of Medical Sciences (CN)
Good health and well-being
Openalex Percentile: Top 34%
Diet and metabolism studies
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