Human <i>ACE2</i> Polymorphisms and Susceptibility to COVID‐19 Infection in the TLSA Cohort
Our findings indicate a possible sex-specific genetic influence of ACE2 polymorphisms on COVID-19 susceptibility, with rs2074192 showing a significant association in females but not in males. These results highlight the need for further research to explore the biological mechanisms underlying this association and its implications for personalized risk assessment and targeted interventions in COVID-19.
Authors
- Thomas Gregor Issac (ORCID: https://orcid.org/0000-0003-3148-3466)
- K. S. Subramaniam
- Jonas S. Sundarakumar (ORCID: https://orcid.org/0000-0002-0877-7936)
- P. K. Das
- Khader Valli Rupanagudi
- Prathima Arvind
- Abhishek Mensegere Lingegodwa
- Gauri S Mullerpattan
- Albert Stezin
- Amitha A CM
- Sohan Angelo A
- Vidhya R
Institutions
- Chinese Institute for Brain Research (CN)
- Bangalore University (IN)
- Indian Institute of Science Bangalore (IN)
- National Brain Research Centre (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_106504
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00