Lecanemab in the real world: First UK experience in the new era of disease modifying treatments for Alzheimer’s disease

This report presents the first real-world experience of lecanemab treatment for AD patients in the UK. Our findings demonstrate feasibility of anti-amyloid therapy in clinical practice, manageable safety profile and early indications of positive patient-reported outcomes. These insights can inform service development and support clinical uptake of novel disease-modifying therapies.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108515
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Lecanemab in the real world: First UK experience in the new era of disease modifying treatments for Alzheimer’s disease

Emer MacSweeney, Avinash Kumar Hari Narayanan
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Lecanemab in the real world: First UK experience in the new era of disease modifying treatments for Alzheimer’s disease

Emer MacSweeney, Avinash Kumar Hari Narayanan
article en

Abstract

This report presents the first real-world experience of lecanemab treatment for AD patients in the UK. Our findings demonstrate feasibility of anti-amyloid therapy in clinical practice, manageable safety profile and early indications of positive patient-reported outcomes. These insights can inform service development and support clinical uptake of novel disease-modifying therapies.

Alzheimer s & DementiaVol. 21(S7)
Department of Health and Social Care (GB)
Openalex Percentile: Top 34%
Alzheimer's disease research and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Lecanemab in the real world: First UK experience in the new era of disease modifying treatments for Alzheimer’s disease — Emer MacSweeney, Avinash Kumar Hari Narayanan · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS