Alzheimer's Disease brain‐ derived Extracellular Vesicles induce cognitive impairment in mice
These findings demonstrate that EVs can carry pathological molecules associated with AD and induce memory impairment that mimics features of the disease. This evidence positions EVs as an important target for AD research and highlights their potential as a novel target for therapeutic strategies in neurodegenerative diseases.
Authors
- Victor Bodart
- Sérgio T. Ferreira (ORCID: https://orcid.org/0000-0001-7160-9866)
- Fernanda G. De Felice
- Mayara Mendonca
- Lisandra Silva Pinheiro
- Rudimar L. Frozza
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Queen's University (CA)
- D’Or Institute for Research and Education (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_099289
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00