Core–shell covalent organic framework-copper nickel disulfide nanoreactors for the synergistic treatment of wound infections
Bacterial biofilms are a major cause of diabetic chronic wound healing failure, with effective solutions still challenging. This study prepares core-shell Cu-NiS<sub>2</sub>@COF@PEG nanoreactors with dual enzyme-like/photothermal effects. <i>In vitro</i> and <i>in vivo</i> studies confirmed that they have multi-mode sterilization, promote collagen deposition, and accelerate angiogenesis to promote healing.
Authors
- Yuzhu Long
- Ziwei Xiang (ORCID: https://orcid.org/0000-0002-2513-2873)
- Yuzhu Yuan
- T. G. Wang
- Junlun Zhu
- Shaojiang Zheng
- Wei Wen
- Xiuhua Zhang
- Shengfu Wang
- Hongmei Deng
- Huayu Xiong
Institutions
- Hubei University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1039/d5cc05801e
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00