Fe(III)-Promoted <i>ortho</i> -Selective C–H Borylation of Aryl Selenoesters
Herein, a novel protocol for the Fe(OTf)<sub>3</sub>-promoted <i>ortho</i>-selective C-H borylation of aryl selenoesters is described. The corresponding borylated selenoesters are obtained with excellent site selectivity in moderate to good yields under mild conditions. The borylated products can be converted to various useful intermediates. Additionally, the differential reactivity of some substrates is illustrated by a detailed density functional theory calculation.
Authors
- Y M Zhang
- Ping Li (ORCID: https://orcid.org/0000-0003-1497-8600)
- Kai Yang (ORCID: https://orcid.org/0000-0002-9527-8974)
- zezhao Liu
- Zijuan Li
- Shen Shan
- Gaorong Wu
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Nankai University (CN)
- Gannan Medical University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1021/acs.orglett.5c04837
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00