Analysis of the Correlation Between Serum Procalcitonin (PCT), C-Reactive Protein (CRP) Levels and the Occurrence/Severity of Bronchopulmonary Dysplasia in ELBW/VLBW Neonates

In this retrospective study, elevated serum PCT and CRP levels were positively associated with the severity of BPD in ELBW/VLBW neonates. The identified risk factors, including intrauterine infection, gestational age <28 weeks, prolonged assisted ventilation, infectious pneumonia, and high FiO<sub>2</sub>, are independently associated with BPD. These findings suggest that monitoring these biomarkers and risk factors may warrant intensified clinical attention.

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Publication Details

Journal
International Journal of General Medicine
Published
2025-12-01
DOI
https://doi.org/10.2147/ijgm.s559764
Primary Topic
Neonatal Respiratory Health Research
Type
article
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article

Analysis of the Correlation Between Serum Procalcitonin (PCT), C-Reactive Protein (CRP) Levels and the Occurrence/Severity of Bronchopulmonary Dysplasia in ELBW/VLBW Neonates

Ming Li, Xian Dong, Jinwen Chen, Jiaan Wang et al.
International Journal of General Medicine
Neonatal Respiratory Health Research
article

Analysis of the Correlation Between Serum Procalcitonin (PCT), C-Reactive Protein (CRP) Levels and the Occurrence/Severity of Bronchopulmonary Dysplasia in ELBW/VLBW Neonates

Ming Li, Xian Dong, Jinwen Chen, Jiaan Wang, Shu Zhang
article en

Abstract

In this retrospective study, elevated serum PCT and CRP levels were positively associated with the severity of BPD in ELBW/VLBW neonates. The identified risk factors, including intrauterine infection, gestational age <28 weeks, prolonged assisted ventilation, infectious pneumonia, and high FiO<sub>2</sub>, are independently associated with BPD. These findings suggest that monitoring these biomarkers and risk factors may warrant intensified clinical attention.

International Journal of General MedicineVol. Volume 18
Third People's Hospital of Hefei (CN), Hefei First People's Hospital (CN), Hefei Infectious Disease Hospital (CN)
Good health and well-being
Openalex Percentile: Top 28%
Neonatal Respiratory Health Research
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