No significant association between self‐reported physical activity and brain volumes in women and men from five European cohorts
Our null findings raise the question of whether self-report questionnaires of physical activity, which commonly feature in big datasets, are sufficiently sensitive to capture a - presumably modest - association between physical activity levels and grey matter outcomes. We conclude that the reliance on self-report questionnaires of physical activity is sub-optimal for brain-behaviour analyses.
Authors
- Anne Theil Gates (ORCID: https://orcid.org/0000-0001-5498-8104)
- Kathrine Skak Madsen (ORCID: https://orcid.org/0000-0001-8884-5902)
- Andreas M. Brandmaier (ORCID: https://orcid.org/0000-0001-8765-6982)
- Julia Binnewies (ORCID: https://orcid.org/0000-0002-9657-2905)
- Øystein Sørensen (ORCID: https://orcid.org/0000-0003-0724-3542)
- Michael Kjær (ORCID: https://orcid.org/0000-0002-4582-8755)
- Rogier Kievit (ORCID: https://orcid.org/0000-0003-0700-4568)
- Kristine B. Walhovd (ORCID: https://orcid.org/0000-0003-1918-1123)
- Carl‐Johan Boraxbekk (ORCID: https://orcid.org/0000-0002-4458-6475)
- Sara Pudas (ORCID: https://orcid.org/0000-0001-9512-3289)
- L. O. NYBERG
- Klaus Ebmeier
- Sana Suri
- William F. C. Baare
- Naiara Demnitz
- Hartwig R Siebner
- Anders M Fjell
Institutions
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- Radboud University Nijmegen (NL)
- University of Oslo (NO)
- Frederiksberg Hospital (DK)
- Hvidovre Hospital (DK)
- Radboud University Medical Center (NL)
- University of Oxford (GB)
- MSB Medical School Berlin (DE)
- Max Planck Institute for Human Development (DE)
- Vrije Universiteit Amsterdam (NL)
- Umeå University (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_097396
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00