Modifiable lifestyle factors are associated with blood‐brain barrier permeability in cognitively normal older adults

Alcohol consumption and physical activity were related to BBB permeability in cognitively normal older adults, with sex-specific patterns warranting further examination. Findings implicate modifiable vascular lifestyle factors in the maintenance of BBB integrity in later life, with potential applications to strategies supporting healthy brain aging.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108722
Primary Topic
Barrier Structure and Function Studies
Type
article
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article

Modifiable lifestyle factors are associated with blood‐brain barrier permeability in cognitively normal older adults

Seraphina K. Solders, Emilie T. Reas
Alzheimer s & Dementia
Barrier Structure and Function Studies
article

Modifiable lifestyle factors are associated with blood‐brain barrier permeability in cognitively normal older adults

Seraphina K. Solders, Emilie T. Reas
article en

Abstract

Alcohol consumption and physical activity were related to BBB permeability in cognitively normal older adults, with sex-specific patterns warranting further examination. Findings implicate modifiable vascular lifestyle factors in the maintenance of BBB integrity in later life, with potential applications to strategies supporting healthy brain aging.

Alzheimer s & DementiaVol. 21(S7)
University of California San Diego (US)
Good health and well-being
Openalex Percentile: Top 39%
Barrier Structure and Function Studies
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