Gene‐centric analysis using functional annotation identifies genetic associations with blood‐based biomarkers of Alzheimer's disease in older adults from India
Rare and common variants in AD- and AD biomarker-associated genes may impact blood levels of AD biomarkers in South Asians. Gene-based analysis may aid in identifying rare deleterious variants not seen in other populations.
Authors
- Eileen M. Crimmins (ORCID: https://orcid.org/0000-0001-5459-5239)
- X. Zhou
- Priya Moorjani (ORCID: https://orcid.org/0000-0002-0947-5673)
- Bharat Thyagarajan (ORCID: https://orcid.org/0000-0001-6968-6985)
- Masroor Anwar (ORCID: https://orcid.org/0000-0001-7529-7388)
- AB Dey
- Peifeng Hu
- Jinkook Lee
- Gerald D. Schellenberg
- Yuk Yee Leung
- Li‐San Wang
- Zheng Li
- Hasan Abu‐Amara
- Sharmistha Dey
- Sharon L R Kardia
- Jennifer A Smith
- Wei Zhao
- Kumarasamy Thangaraj
Institutions
- University of Southern California (US)
- University of Minnesota (US)
- University of California, Los Angeles (US)
- Centre for Cellular and Molecular Biology (IN)
- University of Michigan (US)
- All India Institute of Medical Sciences (IN)
- University of Pennsylvania (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_099411
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00