Engineered Hybrid Nanovesicles Combining Macrophage Membranes and Artificial Lipids for Abdominal Aortic Aneurysm Therapy
These results demonstrate that hybrid biomimetic systems integrating natural cellular components with engineered materials offer a strategic approach for vascular endothelial repair therapy while minimizing off-target effects. This membrane fusion technology establishes a prototype for developing next-generation targeted vascular therapeutics.
Authors
- Weiyao Chen (ORCID: https://orcid.org/0009-0009-0445-8397)
- Jiaxin Hu (ORCID: https://orcid.org/0000-0002-5384-9388)
- Jie Liu (ORCID: https://orcid.org/0000-0002-5354-9633)
- Jiaqi Yu (ORCID: https://orcid.org/0000-0002-6626-2295)
- Zhongnan Xia
- Yuhua Lei
- Heng Wu
- Jiling Zhao
- Shilong Sun
- Hongbo Chen
- Jiamin Xu
Institutions
- Sun Yat-sen University (CN)
- Wenzhou Medical University (CN)
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijn.s565290
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.67