APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells

APOE4 genotype has an impact on vascular cells. Further analysis is ongoing to test drugs to recovery APOE4 barrier functionality and test vascular impact on neuronal health in neurovascular 3D models.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_098686
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells

Taylor Bertucci
Alzheimer s & Dementia
Barrier Structure and Function Studies
article

APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells

Taylor Bertucci
article en

Abstract

APOE4 genotype has an impact on vascular cells. Further analysis is ongoing to test drugs to recovery APOE4 barrier functionality and test vascular impact on neuronal health in neurovascular 3D models.

Alzheimer s & DementiaVol. 21(S1)
Neural Stem Cell Institute (US)
Good health and well-being
Openalex Percentile: Top 39%
Barrier Structure and Function Studies
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

APOE4 alters vascular cells in cognitively normal brains and in vitro models revealing early pathogenic AD contributions of endothelial cells — Taylor Bertucci · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS