Trajectories of Cognitive Decline over 24 months in Older Adults with Treatment‐Resistant Late‐life Depression at risk for Dementia
We have a poor understanding of the role of treatment resistance in increasing dementia risk in LLD. This study showed persistence of depression may predict worse cognitive outcomes in the long-term but may not specifically accelerate cognitive decline in TRLLD.
Authors
- M BUTTERS
- Benoit H. Mulsant (ORCID: https://orcid.org/0000-0002-0303-6450)
- Swathi Gujral (ORCID: https://orcid.org/0000-0003-4775-2106)
- Joshua S. Shimony (ORCID: https://orcid.org/0000-0002-6228-776X)
- Aristotle N. Voineskos (ORCID: https://orcid.org/0000-0003-0156-0395)
- Patrick J. Brown (ORCID: https://orcid.org/0000-0003-3906-6667)
- Ashlyn Runk (ORCID: https://orcid.org/0009-0004-1287-671X)
- Kayla Conaty
- Helen Lavretsky
- Elllie Rapp
- Ana Paula Costa
- Keeley M Scullin
Institutions
- Louisiana State University (US)
- Centre for Addiction and Mental Health (CA)
- University of Pittsburgh (US)
- University of Toronto (CA)
- Washington University in St. Louis (US)
- UCLA Health (US)
- Toronto Dementia Research Alliance (CA)
- University of Pittsburgh Medical Center (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108863
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00