Early‐Life Educational Experiences Moderates the Association Later‐Life Glycemic Level and Memory Trajectories in Later‐Life

The current study provides preliminary evidence suggesting that early-life educational quality, particularly in mathematics and literacy, may shape hyperglycemia-related associations with memory aging. Poor educational experiences during formative years may hinder the development of cognitive reserve, exacerbating the adverse cognitive consequences of hyperglycemia. Future studies are needed to establish causal relationships, examine educational experiences beyond high school, and model memory trajectories over a longer follow-up period, to more fully characterize the contribution of early-life educational experiences to cognitive health in later-life.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_107253
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Early‐Life Educational Experiences Moderates the Association Later‐Life Glycemic Level and Memory Trajectories in Later‐Life

Jacqui Smith, Jennifer J. Manly, A. Zarina Kraal
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Early‐Life Educational Experiences Moderates the Association Later‐Life Glycemic Level and Memory Trajectories in Later‐Life

Jacqui Smith, Jennifer J. Manly, A. Zarina Kraal
article en

Abstract

The current study provides preliminary evidence suggesting that early-life educational quality, particularly in mathematics and literacy, may shape hyperglycemia-related associations with memory aging. Poor educational experiences during formative years may hinder the development of cognitive reserve, exacerbating the adverse cognitive consequences of hyperglycemia. Future studies are needed to establish causal relationships, examine educational experiences beyond high school, and model memory trajectories over a longer follow-up period, to more fully characterize the contribution of early-life educational experiences to cognitive health in later-life.

Alzheimer s & DementiaVol. 21(S6)
University of Michigan (US), Columbia University Irving Medical Center (US), Institute on Aging (US)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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