Pressure-Induced stromal keratopathy immediate recovery after 30-gauge needle paracentesis

PurposePressure-Induced Stromal Keratopathy (PISK) is a rare complication of Laser in situ keratomileusis (LASIK), in which rapid diagnosis and management is crucial to avoid potential severe complications. We report the case of a PISK where the interface fluid disappeared immediately after single 30-gauge needle paracentesis.MethodsA 56-year-old man asked for refractive surgery in his left eye (LE). He reported an old blunt trauma that had required cataract surgery many years before. The endothelial cell count was 1241 cells/mm<sup>2</sup>. After a first uneventful femtoLASIK treatment a refractive error persisted, therefore flap lifting retreatment was performed. At the one-week postoperative evaluation, PISK was detected, with an intraocular pressure (IOP, rebound tonometer) of 14 mmHg at the centre of the cornea and 31 mmHg at the peripheral cornea.ResultsWe immediately performed corneal 30-gauge needle paracentesis, which allowed the IOP to lower. Our patient reported rapid subjective vision improvement within the first 30 min and almost complete fluid absorption from the flap interface was noticed after 3 h. A single topical hypotensive drug was then prescribed to avoid any further IOP rise. Three weeks after the procedure the visual acuity was almost fully restored with only a mild residual refractive error.ConclusionThe ocular paracentesis was effective in treating PISK in this case. It could be considered to achieve a rapid IOP lowering in PISK, followed by topical hypotensive drugs to maintain the result. The rebound tonometer proved to be very effective in obtaining a peripheral IOP measurement in this case.

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Journal
European Journal of Ophthalmology
Published
2025-12-23
DOI
https://doi.org/10.1177/11206721251397687
Primary Topic
Corneal surgery and disorders
Type
article
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article

Pressure-Induced stromal keratopathy immediate recovery after 30-gauge needle paracentesis

Salvatore Tedesco, Roberto Bellucci, Carlo Bellucci, Alessandra Romano et al.
European Journal of Ophthalmology
Corneal surgery and disorders
article

Pressure-Induced stromal keratopathy immediate recovery after 30-gauge needle paracentesis

Salvatore Tedesco, Roberto Bellucci, Carlo Bellucci, Alessandra Romano, Mario Troisi, Paolo Mora
article en

Abstract

PurposePressure-Induced Stromal Keratopathy (PISK) is a rare complication of Laser in situ keratomileusis (LASIK), in which rapid diagnosis and management is crucial to avoid potential severe complications. We report the case of a PISK where the interface fluid disappeared immediately after single 30-gauge needle paracentesis.MethodsA 56-year-old man asked for refractive surgery in his left eye (LE). He reported an old blunt trauma that had required cataract surgery many years before. The endothelial cell count was 1241 cells/mm<sup>2</sup>. After a first uneventful femtoLASIK treatment a refractive error persisted, therefore flap lifting retreatment was performed. At the one-week postoperative evaluation, PISK was detected, with an intraocular pressure (IOP, rebound tonometer) of 14 mmHg at the centre of the cornea and 31 mmHg at the peripheral cornea.ResultsWe immediately performed corneal 30-gauge needle paracentesis, which allowed the IOP to lower. Our patient reported rapid subjective vision improvement within the first 30 min and almost complete fluid absorption from the flap interface was noticed after 3 h. A single topical hypotensive drug was then prescribed to avoid any further IOP rise. Three weeks after the procedure the visual acuity was almost fully restored with only a mild residual refractive error.ConclusionThe ocular paracentesis was effective in treating PISK in this case. It could be considered to achieve a rapid IOP lowering in PISK, followed by topical hypotensive drugs to maintain the result. The rebound tonometer proved to be very effective in obtaining a peripheral IOP measurement in this case.

European Journal of OphthalmologyVol. 36(2)
Instituto da Visão (BR), University of Naples Federico II (IT)
Good health and well-being
Openalex Percentile: Top 31%
Corneal surgery and disorders
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Pressure-Induced stromal keratopathy immediate recovery after 30-gauge needle paracentesis — Salvatore Tedesco, Roberto Bellucci, et al. · European Journal of Ophthalmology (2025) | TGRS Research Map | TGRS