Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection

This study reveals that the small molecular C248, a bioactive peptide of PRDX4, is a new candidate molecule for intervening in LC senescence and confirms that mitochondrial protection is a key strategy for improving age-related testicular dysfunction.

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Publication Details

Journal
Antioxidants
Published
2025-12-22
DOI
https://doi.org/10.3390/antiox15010021
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00

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article

Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection

Ce Gao, Li Gao, Shuning Yuan, Bei Zhang et al.
Antioxidants
Sperm and Testicular Function
article

Bioactive Peptide C248 of PRDX4 Ameliorates the Function of Testicular Leydig Cells via Mitochondrial Protection

Ce Gao, Li Gao, Shuning Yuan, Bei Zhang, YuGui Cui, Nini Wei, Zhengjie Yan, Yan Meng
article en

Abstract

This study reveals that the small molecular C248, a bioactive peptide of PRDX4, is a new candidate molecule for intervening in LC senescence and confirms that mitochondrial protection is a key strategy for improving age-related testicular dysfunction.

AntioxidantsVol. 15(1)
Nanjing Medical University (CN)
Nanjing Medical University
Openalex Percentile: Top 28%
Sperm and Testicular Function
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