Phenomics Study Reveals Predictable Converging Molecular Signatures in CTE, Alzheimer's and Models of Mild TBI
This study unveiled ADRD predictable converging molecular signatures that appear to drive the Tau-TBI interaction conferring both chronic neuropsychiatric impairments and neurodegenerative disease progression, shedding light on the complex etiology of ADRD.
Authors
- Tamanna Jahan Mony
- Marcus Jackson (ORCID: https://orcid.org/0000-0002-3055-0711)
- S Y Chen
- Thi Thao Nguyen (ORCID: https://orcid.org/0000-0002-7204-530X)
- Sally A. Frautschy (ORCID: https://orcid.org/0000-0003-0194-0363)
- R. Li
- Zezong Gu (ORCID: https://orcid.org/0000-0002-2411-7460)
- Pei Liu (ORCID: https://orcid.org/0000-0002-3795-6140)
- Gregory M. Cole
- Jiankun Cui
- Wenyan Yu
Institutions
- University of California, Los Angeles (US)
- Foundation for Psychocultural Research (US)
- Harry S. Truman Memorial Veterans' Hospital (US)
- VA Greater Los Angeles Healthcare System (US)
- University of Missouri (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_099078
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00