Prognostic Value of A/T/N Biomarkers: Comparing Plasma and Imaging Modalities in Alzheimer’s Disease

Imaging biomarkers, particularly tau PET, show superior prognostic accuracy compared to plasma biomarkers, whereas plasma biomarkers offer unique advantages in combination models through neurodegeneration markers. These findings underscore the complementary roles of plasma and imaging biomarkers and emphasize the need for tailored strategies for prognostic modeling in Alzheimer's disease.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108113
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic Value of A/T/N Biomarkers: Comparing Plasma and Imaging Modalities in Alzheimer’s Disease

Yuna Gu, Sohyun Yim, Sang Won Seo, Jihwan Yun
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Prognostic Value of A/T/N Biomarkers: Comparing Plasma and Imaging Modalities in Alzheimer’s Disease

Yuna Gu, Sohyun Yim, Sang Won Seo, Jihwan Yun
article en

Abstract

Imaging biomarkers, particularly tau PET, show superior prognostic accuracy compared to plasma biomarkers, whereas plasma biomarkers offer unique advantages in combination models through neurodegeneration markers. These findings underscore the complementary roles of plasma and imaging biomarkers and emphasize the need for tailored strategies for prognostic modeling in Alzheimer's disease.

Alzheimer s & DementiaVol. 21(S7)
Samsung Medical Center (KR), Kyung Hee University Medical Center (KR), Sungkyunkwan University (KR)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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