Multi‐Target Mechanisms of the Naofucong in Ameliorating Diabetes‐Associated Cognitive Dysfunction via <scp>cAMP</scp> / <scp>PKA</scp> / <scp>CREB</scp> ‐Mediated Synaptic and Inflammatory Regulation

NFC exerts multi-target neuroprotective effects by activating the cAMP/PKA/CREB pathway and coordinately regulating synaptic plasticity and neuroinflammation. These findings highlight NFC as a promising candidate for DACD treatment.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-12-01
DOI
https://doi.org/10.1002/cns.70716
Citations
1
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.84

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article

Multi‐Target Mechanisms of the Naofucong in Ameliorating Diabetes‐Associated Cognitive Dysfunction via cAMP / PKA / CREB ‐Mediated Synaptic and Inflammatory Regulation

Ruiying Yin, Yue Tian, Mengren Zhang, Guangchan Jing et al.
1 citations
CNS Neuroscience & Therapeutics
Neurological Disease Mechanisms and Treatments
0.84
article

Multi‐Target Mechanisms of the Naofucong in Ameliorating Diabetes‐Associated Cognitive Dysfunction via cAMP / PKA / CREB ‐Mediated Synaptic and Inflammatory Regulation

Ruiying Yin, Yue Tian, Mengren Zhang, Guangchan Jing, Mei Ma
article en
1 citations

Abstract

NFC exerts multi-target neuroprotective effects by activating the cAMP/PKA/CREB pathway and coordinately regulating synaptic plasticity and neuroinflammation. These findings highlight NFC as a promising candidate for DACD treatment.

CNS Neuroscience & TherapeuticsVol. 31(12)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Peking Union Medical College
Good health and well-being
Openalex Percentile: Top 19%
Neurological Disease Mechanisms and Treatments
0.84
DOIOpen Access PDFOpenAlex
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