APOE‐ ε4, social determinants of health and Alzheimer's Disease pathology and dementia: findings from the Biobank for Aging Studies
SDH did not modify the association between APOE-ε4 and AD pathology, while it modified the expression of dementia in participants with AD pathology. This association was stronger in individuals with unfavorable compared to favorable SDH profile.
Authors
- Lea T. Grinberg (ORCID: https://orcid.org/0000-0002-6809-0618)
- Renata Elaine Paraízo Leite (ORCID: https://orcid.org/0000-0002-5878-398X)
- Eduardo Ferriolli (ORCID: https://orcid.org/0000-0002-5028-2451)
- Aline Maria Macagnan Ciciliati (ORCID: https://orcid.org/0009-0003-1428-4745)
- Naomi Vidal‐Ferreira
- Vítor Ribeiro Paes (ORCID: https://orcid.org/0000-0001-8752-5624)
- Cláudia Kimie Suemoto (ORCID: https://orcid.org/0000-0002-5942-4778)
- Carlos Augusto Pasqualucci
Institutions
- Universidade de São Paulo (BR)
- University of California, San Francisco (US)
- Universidade Federal Rural da Amazônia (BR)
- Microsoft (Brazil) (BR)
- University Memory and Aging Center (US)
- Global Brain Health Institute (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_105811
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00