Evaluation of the antimicrobial effect of cannabidiol (CBD) in a multispecies subgingival biofilm model
CBD reduced the total bacterial count and the red complex, inhibiting known periodontal pathogens. Within the limitations, the results provide exploratory evidence that CBD may reduce the total bacterial count in the proposed polymicrobial biofilm model, including the red complex bacteria, and may thus be postulated as an inhibitor of known periodontal pathogens. However, future <i>in vivo</i> studies with robust sample sizes and standardized CFU-based quantification are required to confirm these findings.
Authors
- Hernan Garzón (ORCID: https://orcid.org/0000-0001-8320-6220)
- Mayra Alexandra Téllez Corral (ORCID: https://orcid.org/0000-0003-0006-7822)
- L. Suarez
- Roberto Galvão Dinelli
- Bruno Bueno-Silva
- Enzo Pelentir Christoff
- Ursula Modesto Sandi
- Pedro Henrique Moreira Paulo Tolentino
- Manuela Rocha Bueno
- Daniel R Suárez
Institutions
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Pontificia Universidad Javeriana (CO)
- University of Nariño (CO)
- Universidad Nacional de Colombia (CO)
- Methodist University of Piracicaba (BR)
- Universidad Antonio Nariño (CO)
- Guarulhos University (BR)
- Faculdade São Leopoldo Mandic (BR)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1080/20002297.2025.2603706
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00