Maintain Your Brain: recent findings, future challenges
An online platform tailored to individuals' risk factor profiles over three years significantly improved cognition decline in older adults. Despite MYB being effective, scalable, and potentially able to delay dementia onset and cost effective, attracting government or commercial interest to deliver an improved MYB version at a wider population level has proved challenging. Reference 1. Brodaty H, Chau T, Heffernan M et al. An online multidomain lifestyle intervention to prevent cognitive decline in at-risk older adults: a randomized controlled trial. Nature Medicine 2025 doi.org/10.1038/s41591-024-03351-6.
Authors
- Tiffany Chau (ORCID: https://orcid.org/0000-0002-3469-3672)
- Nicola T. Lautenschlager (ORCID: https://orcid.org/0000-0003-4850-7794)
- Michael Millard (ORCID: https://orcid.org/0000-0002-0228-9560)
- Anthony Maeder (ORCID: https://orcid.org/0000-0002-7398-2581)
- John J. McNeil (ORCID: https://orcid.org/0000-0002-1049-5129)
- Jeewani Anupama Ginige (ORCID: https://orcid.org/0000-0002-6695-6983)
- Kaarin Jane Anstey (ORCID: https://orcid.org/0000-0002-9706-9316)
- Maria Fiatarone Singh (ORCID: https://orcid.org/0000-0002-1897-8707)
- Louisa Jorm (ORCID: https://orcid.org/0000-0003-0390-661X)
- Megan Heffernan (ORCID: https://orcid.org/0000-0001-8992-8072)
- H Brodaty
- Perminder S. Sachdev
- Michael Valenzuela
Institutions
- The University of Sydney (AU)
- The University of Melbourne (AU)
- Flinders University (AU)
- UNSW Sydney (AU)
- National Ageing Research Institute (AU)
- St Vincent's Hospital Sydney (AU)
- The George Institute for Global Health (AU)
- ARC Centre of Excellence in Synthetic Biology (AU)
- Monash University (AU)
- Western Sydney University (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_103197
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00