Perioperative Hereditary Angioedema Triggered by Laryngeal Mask Airway: A Case Report and Anesthetic Implications

Hereditary angioedema (HAE) is a rare condition characterized by episodic subcutaneous or mucosal edema, which may pose significant challenges in the perioperative setting. We report the management of a 79‑year-old male patient undergoing transurethral resection of a bladder tumor under general anesthesia with a supraglottic airway device. Postoperatively, the patient developed acute facial edema requiring prompt recognition and disease‑specific intervention. Rapid resolution was achieved, and the patient had an uneventful recovery. This case underscores the importance of perioperative awareness, early recognition, and careful planning to prevent airway complications in patients with HAE.

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Publication Details

Journal
Cureus
Published
2025-12-22
DOI
https://doi.org/10.7759/cureus.99886
Primary Topic
Coagulation, Bradykinin, Polyphosphates, and Angioedema
Type
article
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article

Perioperative Hereditary Angioedema Triggered by Laryngeal Mask Airway: A Case Report and Anesthetic Implications

Marco Giudice, Riccardo Pulitanò, Letizia Isidori, Francesca Romana Misiti et al.
Cureus
Coagulation, Bradykinin, Polyphosphates, and Angioedema
article

Perioperative Hereditary Angioedema Triggered by Laryngeal Mask Airway: A Case Report and Anesthetic Implications

Marco Giudice, Riccardo Pulitanò, Letizia Isidori, Francesca Romana Misiti, Francesca La Verde
article en

Abstract

Hereditary angioedema (HAE) is a rare condition characterized by episodic subcutaneous or mucosal edema, which may pose significant challenges in the perioperative setting. We report the management of a 79‑year-old male patient undergoing transurethral resection of a bladder tumor under general anesthesia with a supraglottic airway device. Postoperatively, the patient developed acute facial edema requiring prompt recognition and disease‑specific intervention. Rapid resolution was achieved, and the patient had an uneventful recovery. This case underscores the importance of perioperative awareness, early recognition, and careful planning to prevent airway complications in patients with HAE.

CureusVol. 17(12)
Azienda Ospedaliera San Giovanni Addolorata (IT)
Good health and well-being
Openalex Percentile: Top 27%
Coagulation, Bradykinin, Polyphosphates, and Angioedema
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Perioperative Hereditary Angioedema Triggered by Laryngeal Mask Airway: A Case Report and Anesthetic Implications — Marco Giudice, Riccardo Pulitanò, et al. · Cureus (2025) | TGRS Research Map | TGRS