Modulating TFEB lysosomal function for aging and Alzheimer's disease

These findings position TFEB as a promising target for interventions in aging and neurodegeneration and highlight the IKK-TFEB axis as a therapeutic entry point in Alzheimer's pathology.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108380
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
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article

Modulating TFEB lysosomal function for aging and Alzheimer's disease

Marco Sardiello
Alzheimer s & Dementia
Autophagy in Disease and Therapy
article

Modulating TFEB lysosomal function for aging and Alzheimer's disease

Marco Sardiello
article en

Abstract

These findings position TFEB as a promising target for interventions in aging and neurodegeneration and highlight the IKK-TFEB axis as a therapeutic entry point in Alzheimer's pathology.

Alzheimer s & DementiaVol. 21(S7)
Washington University in St. Louis (US)
Openalex Percentile: Top 30%
Autophagy in Disease and Therapy
DOIOpen Access PDFOpenAlex
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Modulating TFEB lysosomal function for aging and Alzheimer's disease — Marco Sardiello · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS