Impact of sperm fractionation on chromosome positioning, chromatin integrity, DNA methylation, and hydroxymethylation level
Our findings underline the validity of methods used for selection of high-quality spermatozoa in assisted reproductive technologies (ART), also in the context of the sperm chromosomal topology and chromatin integrity, crucial at the first steps during fertilization.
Authors
- Maciej Kurpisz (ORCID: https://orcid.org/0000-0003-3275-3245)
- Michał Frączek
- Zuzanna Graczyk (ORCID: https://orcid.org/0009-0003-3395-4855)
- Julia Pospieszna (ORCID: https://orcid.org/0000-0001-5727-1563)
- Zuzanna Myslicka
- Marta Olszewska
- Marzena Kamieniczna
- Jagoda Kostyk
Institutions
- Poznan University of Medical Sciences (PL)
- Institute of Human Genetics (PL)
- Institute of Plant Genetics, Polish Academy of Sciences (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s11658-025-00830-7
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu