Blood N‐glycomics reveals individuals at risk for cognitive decline and Alzheimer’s disease
Here, we provided an extensive characterization of the blood N-glycome in AD. We showed that the blood N-glycome could predict cognitive decline in an amyloid/tau independent manner. Blood N-glycomics should be further developed as a minimally invasive prognostic biomarker in early stages of dementia.
Authors
- Stefan Gaunitz (ORCID: https://orcid.org/0000-0003-4646-054X)
- Sophia Schedin Weiss
- Robin Ziyue Zhou (ORCID: https://orcid.org/0000-0002-3379-1430)
- B. Winblad
- Anders Sköldunger (ORCID: https://orcid.org/0000-0001-8439-2248)
- Anders B. Wimo
- Lars O Tjernberg
- Tormod Fladby
Institutions
- Karolinska University Hospital (SE)
- University of Oslo (NO)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108302
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00