The Impact of Comorbid Depression on Cognitive Reserve in Patients with Alzheimer’s Disease: A Case‐Control Study

The depression in AD patients is associated with reduced cognitive reserve, which may increase vulnerability to more accelerated cognitive decline. These findings suggest that intervention of depressive symptoms may be implicated in the preservation of cognitive resilience in AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108988
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The Impact of Comorbid Depression on Cognitive Reserve in Patients with Alzheimer’s Disease: A Case‐Control Study

Amira A. Shahin, Mohamed Khaled Ali Mohamed Ali Zid, Mohamed Hosni Kamel Elkellawi
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

The Impact of Comorbid Depression on Cognitive Reserve in Patients with Alzheimer’s Disease: A Case‐Control Study

Amira A. Shahin, Mohamed Khaled Ali Mohamed Ali Zid, Mohamed Hosni Kamel Elkellawi
article en

Abstract

The depression in AD patients is associated with reduced cognitive reserve, which may increase vulnerability to more accelerated cognitive decline. These findings suggest that intervention of depressive symptoms may be implicated in the preservation of cognitive resilience in AD.

Alzheimer s & DementiaVol. 21(S7)
Cairo University (EG)
Quality Education
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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The Impact of Comorbid Depression on Cognitive Reserve in Patients with Alzheimer’s Disease: A Case‐Control Study — Amira A. Shahin, Mohamed Khaled Ali Mohamed Ali Zid, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS