Proteomic Analysis of NULISA™ plasma analytes and Associations with Neurocognitive measures and Incident Dementia in older adults
Proteins subserving functions related to synaptic vesicle exocytosis and inflammation were associated with cognition and incident dementia in the ARIC sample, but power is limited to evaluate the full range of proteins. Future investigations should increase the sample size to identify other novel proteomic pathways related to cognition and incident dementia.
Authors
- Hubert Leo
- Omonigho M. Bubu (ORCID: https://orcid.org/0000-0001-7438-2628)
- Joshua L. Gills (ORCID: https://orcid.org/0000-0003-3321-4120)
Institutions
- NYU Langone Health (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110194
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00