Multi-site thiolation enables rapid and precise synthesis of 2-pyridone thioethers

I 2 - and Ru 3 (CO) 12 /I 2 -catalyzed protocols enable tunable, regioselective multisite thiolation of 2-pyridones with disulfides, allowing access to C3-, C5-, C3,C5-, and C3,C6-thiolated products.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-12-23
DOI
https://doi.org/10.1039/d5qo01352f
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
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article

Multi-site thiolation enables rapid and precise synthesis of 2-pyridone thioethers

Shuangliang Zhao, Guan Huang, Taoyuan Liang, Zhuan Zhang et al.
Organic Chemistry Frontiers
Sulfur-Based Synthesis Techniques
article

Multi-site thiolation enables rapid and precise synthesis of 2-pyridone thioethers

Shuangliang Zhao, Guan Huang, Taoyuan Liang, Zhuan Zhang, Xingchi Li
article en

Abstract

I 2 - and Ru 3 (CO) 12 /I 2 -catalyzed protocols enable tunable, regioselective multisite thiolation of 2-pyridones with disulfides, allowing access to C3-, C5-, C3,C5-, and C3,C6-thiolated products.

Organic Chemistry FrontiersVol. 13(4)
Guangxi University (CN)
Openalex Percentile: Top 33%
Sulfur-Based Synthesis Techniques
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Multi-site thiolation enables rapid and precise synthesis of 2-pyridone thioethers — Shuangliang Zhao, Guan Huang, et al. · Organic Chemistry Frontiers (2025) | TGRS Research Map | TGRS