LINC00519 promotes the progression of cholangiocarcinoma through regulating the axis of miR-876-3p/GATA1

LINC00519 upregulation may serve as a potential indicator of CCA aggravation. LINC00519 promoted CCA development by targeting miR-876-3p to affect cancer cell activities. GATA1, a potential target of miR-876-3p, suggests the potential underlying molecular pathway. Targeting LINC00519 could be an efficient way to manage CCA.

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Publication Details

Journal
Discover Oncology
Published
2025-12-22
DOI
https://doi.org/10.1007/s12672-025-04140-4
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

LINC00519 promotes the progression of cholangiocarcinoma through regulating the axis of miR-876-3p/GATA1

Lina Huang, Kaixuan Hui, Zhenlong Chai, Xiao Yang
Discover Oncology
Cholangiocarcinoma and Gallbladder Cancer Studies
article

LINC00519 promotes the progression of cholangiocarcinoma through regulating the axis of miR-876-3p/GATA1

Lina Huang, Kaixuan Hui, Zhenlong Chai, Xiao Yang
article en

Abstract

LINC00519 upregulation may serve as a potential indicator of CCA aggravation. LINC00519 promoted CCA development by targeting miR-876-3p to affect cancer cell activities. GATA1, a potential target of miR-876-3p, suggests the potential underlying molecular pathway. Targeting LINC00519 could be an efficient way to manage CCA.

Discover OncologyVol. 16(1)
Jiangsu University (CN)
Good health and well-being
Openalex Percentile: Top 27%
Cholangiocarcinoma and Gallbladder Cancer Studies
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LINC00519 promotes the progression of cholangiocarcinoma through regulating the axis of miR-876-3p/GATA1 — Lina Huang, Kaixuan Hui, et al. · Discover Oncology (2025) | TGRS Research Map | TGRS