Amygdala stimulation promotes memory recovery and synaptic plasticity in Alzheimer's disease genetic animal model 5XFAD

Combination MWM plus BLA stimulation is able to induce plasticity related mechanisms involved in learning and memory but also in functional recovery, which produces skill-memory recovery in the 5XFAD mice. This result opens a path in the search for neurological restoration based on the plasticity of memory loss in Alzheimer's disease.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_096825
Primary Topic
Memory and Neural Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Amygdala stimulation promotes memory recovery and synaptic plasticity in Alzheimer's disease genetic animal model 5XFAD

Felipe Conejera, William Almaguer, Luis Tabilo, Daymara Mercerón et al.
Alzheimer s & Dementia
Memory and Neural Mechanisms
article

Amygdala stimulation promotes memory recovery and synaptic plasticity in Alzheimer's disease genetic animal model 5XFAD

Felipe Conejera, William Almaguer, Luis Tabilo, Daymara Mercerón, Paulina Puebla, Alvaro Ardiles
article en

Abstract

Combination MWM plus BLA stimulation is able to induce plasticity related mechanisms involved in learning and memory but also in functional recovery, which produces skill-memory recovery in the 5XFAD mice. This result opens a path in the search for neurological restoration based on the plasticity of memory loss in Alzheimer's disease.

Alzheimer s & DementiaVol. 21(S1)
International Center of Neurologic Restoration (CU), University of Valparaíso (CL)
Openalex Percentile: Top 33%
Memory and Neural Mechanisms
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