Integrated Transcriptomic Analysis Leveraging Single-Cell and Bulk RNA Sequencing Data to Uncover Pyroptosis-Related Prognostic Signatures in HCC

This study uniquely integrates single-cell and bulk transcriptomic data to systematically identify pyroptosis-related prognostic biomarkers, pinpointing their cellular origin within the tumor microenvironment.

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Publication Details

Journal
Journal of Hepatocellular Carcinoma
Published
2025-12-01
DOI
https://doi.org/10.2147/jhc.s557035
Primary Topic
Inflammasome and immune disorders
Type
article
Field-Weighted Citation Impact
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article

Integrated Transcriptomic Analysis Leveraging Single-Cell and Bulk RNA Sequencing Data to Uncover Pyroptosis-Related Prognostic Signatures in HCC

Zhijia Sun, Yupeng Di, Xiaoli Kang, Zhuo Song et al.
Journal of Hepatocellular Carcinoma
Inflammasome and immune disorders
article

Integrated Transcriptomic Analysis Leveraging Single-Cell and Bulk RNA Sequencing Data to Uncover Pyroptosis-Related Prognostic Signatures in HCC

Zhijia Sun, Yupeng Di, Xiaoli Kang, Zhuo Song, Jiangbo Li
article en

Abstract

This study uniquely integrates single-cell and bulk transcriptomic data to systematically identify pyroptosis-related prognostic biomarkers, pinpointing their cellular origin within the tumor microenvironment.

Journal of Hepatocellular CarcinomaVol. Volume 12
United States Air Force (US), Institute of Biophysics (CN), Air Force General Hospital PLA (CN)
Openalex Percentile: Top 37%
Inflammasome and immune disorders
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