Beyond Images : Seeing the unseen for early detection of Alzheimer's Disease

Utilizing the outputs of the MRI-imaging model and CSF sample model, we estimated approximately when a patient may enter stages of Low and Moderate ADNC, potentially helping reveal the otherwise 'missed period of intervention'. This could result in faster treatments for patients still in a treatable phase of their disease, and provide a model for understanding disease progression overtime. Finally, computing a salience map we can potentially determine plaque, NFT, and other biomarkers' locations, enabling higher treatment accuracy, thus more 'personalized' treatment for patients.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108065
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond Images : Seeing the unseen for early detection of Alzheimer's Disease

Shivam Joshi‐Awasthi
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Beyond Images : Seeing the unseen for early detection of Alzheimer's Disease

Shivam Joshi‐Awasthi
article en

Abstract

Utilizing the outputs of the MRI-imaging model and CSF sample model, we estimated approximately when a patient may enter stages of Low and Moderate ADNC, potentially helping reveal the otherwise 'missed period of intervention'. This could result in faster treatments for patients still in a treatable phase of their disease, and provide a model for understanding disease progression overtime. Finally, computing a salience map we can potentially determine plaque, NFT, and other biomarkers' locations, enabling higher treatment accuracy, thus more 'personalized' treatment for patients.

Alzheimer s & DementiaVol. 21(S7)
William Penn University (US)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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