The effect of probiotic supplementation in older adults with mild cognitive impairment and Alzheimer’s disease: A triple‐blind, randomized, placebo‐controlled clinical trial

These findings suggest that probiotic supplementation influenced levels of TNF-α, GDNF, and NGF, underscoring the importance of clinical research into the role of gut microbiota in maintaining brain health.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108842
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

The effect of probiotic supplementation in older adults with mild cognitive impairment and Alzheimer’s disease: A triple‐blind, randomized, placebo‐controlled clinical trial

Adrielly Vargas Lídio, TATIANA BARICHELLO, Gabriela Serafim Keller, Eduarda Behenck Medeiros et al.
Alzheimer s & Dementia
Gut microbiota and health
article

The effect of probiotic supplementation in older adults with mild cognitive impairment and Alzheimer’s disease: A triple‐blind, randomized, placebo‐controlled clinical trial

Adrielly Vargas Lídio, TATIANA BARICHELLO, Gabriela Serafim Keller, Eduarda Behenck Medeiros, Luize do Canto Velho, Gabriela Piovesan Fenilli, Débora Dagostin Casagrande, Bruno Kluwe‐Schiavon, Josiane Budni, Carolina Speling Mendes Souza
article en

Abstract

These findings suggest that probiotic supplementation influenced levels of TNF-α, GDNF, and NGF, underscoring the importance of clinical research into the role of gut microbiota in maintaining brain health.

Alzheimer s & DementiaVol. 21(S7)
Centro Universitário do Espírito Santo (BR), Universidade do Extremo Sul Catarinense (BR), The University of Texas Health Science Center at Houston (US)
Good health and well-being
Openalex Percentile: Top 37%
Gut microbiota and health
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