An AIE photosensitizer with type I/II ROS generation for photodynamic therapy of toxoplasmosis
Toxoplasmosis, a global parasitic disease threatening one-third of humans, lacks effective treatments. We developed a mitochondrion-targeting AIE photosensitizer (AIEPS) generating dual type I/II ROS, enabling light-activated eradication of <i>Toxoplasma gondii</i> and offering a potent photodynamic therapy against toxoplasmosis.
Authors
- Jiating Chen
- Peng Zhang (ORCID: https://orcid.org/0000-0002-2774-5534)
- Jihong Chen
Institutions
- Tianjin University of Science and Technology (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Institutes of Advanced Technology (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1039/d5cc04690d
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00