Lessons Learned in Study Recruitment from a Randomized Controlled Clinical Trial for Alzheimer's Disease Prevention

Recruitment from hospital databases yielded the largest randomization rate of 31%. The primary reason for phone screening and post-consent exclusion is SBP <130 mmHg, which suggests that the current recruitment strategies likely have reached to a population with normal or well-controlled blood pressure. Thus, IPAT enrollment should consider recruiting from underserved populations who have limited access to blood pressure management such as from the socioeconomically disadvantaged minority groups or from rural communities.