A device profile of the SynCardia temporary total artificial heart as a bridge-to-transplantation in patients with biventricular failure

TAH offers full heart replacement and is evolving toward becoming a long-term alternative to transplants. Challenges like power supply, long-term durability, and biocompatibility are being addressed through innovations such as fully implantable systems and hybrid biological-mechanical designs. Unlike transplantation, TAHs avoid immunosuppression and offer hope to patients who cannot wait for donor hearts.In the coming years, global development of advanced TAHs, coupled with better clinical acceptance could transform treatment of end-stage heart failure providing a more accessible, reliable, and life-sustaining solution.

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Publication Details

Journal
Expert Review of Medical Devices
Published
2025-12-23
DOI
https://doi.org/10.1080/17434440.2025.2606884
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
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article

A device profile of the SynCardia temporary total artificial heart as a bridge-to-transplantation in patients with biventricular failure

Jamal Mahar, Anusha Sunkara, Sowjanya Yenigalla, Modesto J. Colón et al.
Expert Review of Medical Devices
Mechanical Circulatory Support Devices
article

A device profile of the SynCardia temporary total artificial heart as a bridge-to-transplantation in patients with biventricular failure

Jamal Mahar, Anusha Sunkara, Sowjanya Yenigalla, Modesto J. Colón, Francisco A. Arabia, Gabrielle Rubin
article en

Abstract

TAH offers full heart replacement and is evolving toward becoming a long-term alternative to transplants. Challenges like power supply, long-term durability, and biocompatibility are being addressed through innovations such as fully implantable systems and hybrid biological-mechanical designs. Unlike transplantation, TAHs avoid immunosuppression and offer hope to patients who cannot wait for donor hearts.In the coming years, global development of advanced TAHs, coupled with better clinical acceptance could transform treatment of end-stage heart failure providing a more accessible, reliable, and life-sustaining solution.

Expert Review of Medical DevicesVol. 23(1)
University of Arizona (US)
Openalex Percentile: Top 43%
Mechanical Circulatory Support Devices
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