A device profile of the SynCardia temporary total artificial heart as a bridge-to-transplantation in patients with biventricular failure
TAH offers full heart replacement and is evolving toward becoming a long-term alternative to transplants. Challenges like power supply, long-term durability, and biocompatibility are being addressed through innovations such as fully implantable systems and hybrid biological-mechanical designs. Unlike transplantation, TAHs avoid immunosuppression and offer hope to patients who cannot wait for donor hearts.In the coming years, global development of advanced TAHs, coupled with better clinical acceptance could transform treatment of end-stage heart failure providing a more accessible, reliable, and life-sustaining solution.
Authors
- Jamal Mahar (ORCID: https://orcid.org/0000-0001-5801-1448)
- Anusha Sunkara (ORCID: https://orcid.org/0000-0002-1077-7097)
- Sowjanya Yenigalla (ORCID: https://orcid.org/0000-0003-2500-4000)
- Modesto J. Colón
- Francisco A. Arabia
- Gabrielle Rubin
Institutions
- University of Arizona (US)
Publication Details
- Journal
- Expert Review of Medical Devices
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1080/17434440.2025.2606884
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00