Associations of frailty with neuropsychiatric symptoms of Alzheimer's Disease: a longitudinal study

Frailty was associated with NPSs such as depression, anxiety, and apathy among MCI, AD, and cognitive progression participants. Atrophy of the hippocampus and whole brain, as well as peripheral immunity may be involved in the potential mechanisms underlying the above associations.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_100895
Primary Topic
Frailty in Older Adults
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of frailty with neuropsychiatric symptoms of Alzheimer's Disease: a longitudinal study

Lu Tan, Jin‐tai Yu, Hao‐chen Chi
Alzheimer s & Dementia
Frailty in Older Adults
article

Associations of frailty with neuropsychiatric symptoms of Alzheimer's Disease: a longitudinal study

Lu Tan, Jin‐tai Yu, Hao‐chen Chi
article en

Abstract

Frailty was associated with NPSs such as depression, anxiety, and apathy among MCI, AD, and cognitive progression participants. Atrophy of the hippocampus and whole brain, as well as peripheral immunity may be involved in the potential mechanisms underlying the above associations.

Alzheimer s & DementiaVol. 21(S6)
Qingdao University (CN), Qingdao Municipal Hospital (CN), Huashan Hospital (CN)
Openalex Percentile: Top 35%
Frailty in Older Adults
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