Investigating the therapeutic efficacy of physical exercise on tumor immunity in a mouse model of malignant colon cancer
This study confirms that exercise training exerts anti-tumor effects by remodeling the tumor immune microenvironment, activating systemic immune responses, and reducing ctDNA burden. Its unique "immune normalization" effect provides important evidence for the development of "exercise-immunotherapy" combination treatment strategies.
Authors
- Na Ma
- Ying Huang (ORCID: https://orcid.org/0000-0003-4246-1895)
- Wengang Ren
Institutions
- Chengdu Sport University (CN)
- Shenyang Sport University (CN)
- Hebei Institute of Physical Education (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1080/08923973.2025.2600941
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00